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Future of Medicine: Ageing and Dementia – Friend or Foe? 醫療新趨勢: 老齡化和認知退化 – 是敵? 是友?

-Day 2 15:30-16:30 Summit Stage

Speakers

Prof Richard CHOU

周振華教授

Professor, Dartmouth-Hitchcock Medical Center
達特茅斯-希區柯克醫療中心教授


The term “aging” refers to a multitude of physiological or psychological events that occur as we get older. Most of the physiological changes are multifactorial: some are events programmed into our DNA, while others are environmental. Different theories have been put forward to explain the genetically programmed events that contribute to aging, including DNA methylation and telomere shortening.  On the other hand, there are contributing environmental factors including calorie restriction, stress, underlying medical conditions, etc.

Dementia is a gradual loss of memory and other cognitive functions that becomes more prominent over time. All forms of dementia have known causes, whether they be related to genetic changes or environmental factors. The most common form of dementia is Alzheimer’s disease, thought to be caused by beta-amyloid peptide and tau protein deposition, followed by vascular dementia. The correlation between aging and dementia is unknown. Our future lies in our ability to detect diseases at a very early stage or even before they occur, and anticipate how patients will respond to different therapies.  And it will be the focus on our discussion during the conference.

“衰老”是指當我們隨著年齡增加時,機體的生理和心理所發生的眾多變化過程。絕大多數生理變化是多因素影響的,包括我們DNA水平上的變化,環境因素的變化等。現時已有各種不同的理論提出,來解釋基因水平上對衰老產生影響的原因,包括DNA甲基化和端粒縮短。另一方面,環境因素也有很大影響,其中包括熱量限制攝入、壓力、潛在的其他疾病等等。

“癡呆症”是隨著時間發展而逐漸顯現病症的一種疾病,體現在記憶力減退和認知功能的逐漸喪失。所有類型的癡呆症都具有相關已知的致病原因,或與基因變化有關,或受環境因素的影響。最常見的癡呆症為阿爾茨海默症,主要是由β澱粉樣肽和Tau蛋白的沉積引起,并伴有血管性癡呆。

衰老和癡呆症之間的關係暫時是未知的。將來寄希望於我們能夠在很早期階段、甚至于發病前,進行疾病的檢測,以及預測病人對不同治療方案的反應情況。這也將是此次會議我們著重討論的部分。

 

Bio

Professor Chou, a neuroscientist as well as board certified physician in both Internal Medicine and Rheumatology works as the faculty and physician-scientist at Geisel School of Medicine at Dartmouth, a major teaching hospital Dartmouth-Hitchcock Medical Center in USA.  Richard received his specialty training in Rheumatology at Massachusetts General Hospital and Harvard Medical School and later became the Instructor in Medicine at Harvard Medical School.  

周教授是醫學科學家及神經學研究員,就職于達特茅斯蓋瑟,設立自己的實驗室。醫學院是美國達特茅斯-希區柯克醫療中心的主要教學醫院。 他同時也是內科及風濕病科的認證醫師。 他在麻薩諸塞州總醫院及哈佛醫學院接受風濕病科的專科訓練。晉身為哈佛醫學院醫學教員。

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Dr David Lok Kwan, DAI

戴樂群醫生

Chairman, Hong Kong Alzheimer’s Disease Association

香港認知障礙症協會主席

 

Ageing and Dementia in Hong Kong

The graying of society is paralleled by an increasing prevalence of older persons with dementia. We are experiencing a tsunami best described as “Ageing of the Aged” which means that the proportion of those in their 60s will decrease, while those above 70 will exponentially increase.
Among the 80s, 30-40% may be suffering from Alzheimer’s disease and related disorders. Hong Kong must prepare to live with and survive this tsunami on the three levels of prevention, including early diagnosis and intervention, midlife intervention, and bettering our next generation’s brain health. Building a dementia friendly community should be our immediate high priority goal. Everyone need to be geared towards enriching our older population and enabling persons with dementia and their families to live a better life.

高齡化的香港與認知障礙症
香港高速步入高齡化,因此高齡人口患上認知障礙症的比例亦在急劇增長,我們可用高齡化人口中的「高齡化海嘯」來形容,意思是指60歳的組別在長者群眾中的比例將減少,70歳的組別呈幾何級數上升,而80歳以上的組別中,30-40%可能患有認知障礙症或相關疾病。香港必須從三個層面去戰勝這個海嘯:早期的分析和干預性診斷,中年期的干預性診斷,及改善下一代的大腦儲備。 我們應該把社區優化成為認知障礙症友善社區鎖定為高度優先目標,這樣,社會各層面便更能裝備好,令日漸增多的認知障礙症患者及其家人,更安然面對和過比較有質素的生活。

 

Bio

Dr Dai is the Clinical Director for Healthcare for the Senior at Qualigenics. He was the Consultant Geriatrician at Prince of Wales Hospital and taught in The Chinese University of Hong Kong and the University of Hong Kong.  Dr Dai is the Chairman of the Hong Kong Alzheimer’s Disease Association. He obtained his LLB and became an accredited mediator in 2010. He also chairs the Independent Committee for Handling Complaints of the Social Welfare Department from 2015.

戴樂群醫生是確進醫療中心的長者醫療健康總監,曾任威爾斯親王醫院的老人科顧問醫生,並分別曾在香港中文大學和香港大學授課。戴醫生是現任香港認知障礙症協會主席;於2010年獲得法學學士學位,並於同年獲委任為調解員;由2015年起擔任社會福利署整筆撥款獨立處理投訴委員會主席。

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Panel Host

Dr Hong FUNG
馮康醫生

Executive Director and Chief Executive Officer of CUHK Medical Centre

Honorary Professor at Jockey Club School of Public Health and Primary Care, CUHK
香港中文大學醫院執行董事及行政總裁

香港中文大學賽馬會公共衞生及基層醫療學院榮譽教授

 

Bio

Dr Hong FUNG is Chief Executive Officer of CUHK Medical Centre (CUHKMC). Dr Fung was Cluster Chief Executive of the New Territories East Cluster and Hospital Chief Executive of the Prince of Wales Hospital at the Hospital Authority from 2002 to 2013.

馮康醫生為香港中文大學醫院行政總裁,他於2002-2013年間擔任醫管局新界東醫院聯網的聯網總監及威爾斯親王醫院的行政總監。

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